Interferon treatment in hepatitis B virus-associated membranous glomerulopathy
✍ Scribed by S. Kavukçu; G. Ba§demir; Y. Eroğlu; M. Türkmen; F. Eser; B. Büyükgebiz
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 354 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0931-041X
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The first case of hepatitis B-associated membranous glomerulonephritis was described by Combes et al. in 1971 (1). Since that time, numerous other cases have been reported and were reviewed recently (2). In many cases, HBsAg or HBeAg has been detected in immune complexes along the glomerular capilla
## Background: The pathogenetic mechanisms by which individuals with chronic hepatitis b virus (hbv) infection develop membranous nephropathy (mn) are probably dependent on interactions between viral, host and environmental factors; some evidence suggests a genetic predisposition. hbvmn constitutes
Two patients with chronic type B hepatitis and intercurrent episodes of acute type A hepatitis are presented. Serological markers of hepatitis B virus replication decreased or became undetectable in both patients during the acute illness, while interferon activity was transiently detected in serum.