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Interferon-inhibited human osteosarcoma xenografts induce host bone in nude mice

✍ Scribed by Simon Forster; James T. Triffitt; Henrik C.F. Bauer; Otte Brosjö; Olle S. Nilsson; Roger Smith; Bryan Sykes

Book ID
112118321
Publisher
American Society for Bone and Mineral Research
Year
2009
Tongue
English
Weight
554 KB
Volume
3
Category
Article
ISSN
0884-0431

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Murine interferon (IFN) inhibited the growth of 3/3 human tumour xenografts growing in nude mice. This inhibition was independent of the sensitivity of the xenograft to human IFN. In contrast to human IFN, the murine IFN did not directly affect the human tumour cells in vitro as measured by levels o