Interfacing a Fiber-Optic Probe to a Diode Array UV-Visible Spectrophotometer for Drug Dissolution Tests
β Scribed by Brown, Chris W.; Lin, Jie
- Book ID
- 115362132
- Publisher
- Society for Applied Spectroscopy
- Year
- 1993
- Tongue
- English
- Weight
- 376 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0003-7028
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## Abstract This article describes the use of a multichannel UVβVIS detector coupled onβline to an HPLC instrument. Simultaneous measurements of the absorption of a compound over a full range of wavelengths (200β800 nm) makes this almost universal detector a useful tool in screening for unknown com
An automated system for on-line determination of the dissolution rates of drug-delivery formulations to USP Methods I and II is described. The system employs UV-vis spectroscopy utilizing either a fiber-optic probe for direct determination or the option of on-line flow through analysis with prior fi