Chromatin is a highly dynamic structure that acts alternately as a substrate and a template in a number of critical biological processes. Modification of chromatin is pertinent and is responsible for a number of nuclear processes, including DNA repair, replication, transcription, and recombination.
โฆ LIBER โฆ
Interfaces Between the Detection, Signaling, and Repair of DNA Damage
โ Scribed by Rouse, J.
- Book ID
- 111863935
- Publisher
- American Association for the Advancement of Science
- Year
- 2002
- Tongue
- English
- Weight
- 297 KB
- Volume
- 297
- Category
- Article
- ISSN
- 0036-8075
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## Abstract Bulky DNA damage is corrected by the nucleotide excision repair (NER) pathway. Although the core biochemical mechanism of NER is understood, details including lesion recognition and repair in the context of chromatin remain to be elucidated. As more data become available, the complexity
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## Abstract Schematic to illustrate proposed model for lesion detection in chromatin by Kristi L. Jones et al., pp. 803โ811.