Interactive simulator for pharmacokinetics of repetitive drug dosing

✍ Scribed by Glenn A. Iben; Julius H. Anderson

• Book ID: 103050819
• Publisher: Elsevier Science
• Year: 1975
• Weight: 561 KB
• Volume: 4
• Category: Article
• ISSN: 0010-468X
• DOI: 10.1016/0010-468x(75)90013-6

✦ Synopsis

DRUGSIM is a highly interactive program allowing simulation of the effects of repeated drug administration by a variety of routes on plasma concentrations of drugs over a period of time. Drug parameters are read from a data file; prescriptions are obtained from the user at various points during run time. The results for one or two compartment pharmacokinetics are plotted on a storage display tube, and the user is queried for further prescriptions. Simulation involves a point-slope method with a variable time step. The program is written in Fortran IV and run on a DEC PDP-10 computer using a Computek 611 display terminal.