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Pharmacokinetic analysis of drug concentration data obtained during repetitive drug administration

✍ Scribed by Wayne A. Colburn; Milo Gibaldi


Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
455 KB
Volume
66
Category
Article
ISSN
0022-3549

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Use of MULTDOS for pharmacokinetic analy
✍ Wayne A. Colburn; Milo Gibaldi πŸ“‚ Article πŸ“… 1978 πŸ› John Wiley and Sons 🌐 English βš– 231 KB

MULTDOS, a computer method to curve fit data obtained on multiple dosing, was used with either the 1969 or 1974 version of the NONLIN program to compare the pharmacokinetic parameters of ethosuximide during repetitive administration of single or divided daily doses. Elimination rate constants, excre