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Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor

✍ Scribed by Mariarosaria Naddeo; Luigi Vitagliano; Aniello Russo; Giovanni Gotte; Giuseppe D’Alessio; Salvatore Sorrentino

Book ID
116465544
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
297 KB
Volume
579
Category
Article
ISSN
0014-5793

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Interaction of semisynthetic variants of
Interaction of semisynthetic variants of RNase A with ribonuclease inhibitor
✍ Ulf Neumann; Jan Hofsteenge 📂 Article 📅 2008 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 983 KB

## Abstract Derivatives of ribonuclease A (RNase A) with modifications in positions 1 and/or 7 were prepared by subtilisincatalyzed semisynthesis starting from synthetic RNase 1‐20 peptides and S‐protein (RNase 21‐124). The lysyl residue at position 1 was replaced by alanine, whereas Lys‐7 was repl