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Interactions of putative heparin-binding domains of basic fibroblast growth factor and its receptor, FGFR-1, with heparin using synthetic peptides

✍ Scribed by Lisa Kinsella; Hai-Lan Chen; John A Smith; Philip S Rudland; David G Fernig


Book ID
110244939
Publisher
Springer US
Year
1998
Tongue
English
Weight
133 KB
Volume
15
Category
Article
ISSN
1573-4986

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## Abstract Fibroblast growth factor (FGF)‐2 regulates a variety of cellular functions, such as proliferation and differentiation, by binding to cell surface FGF receptors (FGFRs) in the presence of heparin proteoglycans. FGF‐2 is known as a heparin‐binding growth factor, but the localization of th