Interactions of human mast cell tryptase with biological protease inhibitors
β Scribed by Stephen C. Alter; Johannes A. Kramps; Aaron Janoff; Lawrence B. Schwartz
- Book ID
- 115708345
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 860 KB
- Volume
- 276
- Category
- Article
- ISSN
- 0003-9861
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
From a library of 23 N-substituted title compounds, e.g. (I) and (II), derivative (Id) emerges as most potent and selective tryptase inhibitor besides derivatives (Ib) and (Ic). -(COMBRINK, KEITH D.; GUELGEZE,
Protease activated receptors (PARs) compose a family of G protein signal transduction receptors activated by proteolysis. In this study, the susceptibility of PARs expressed on human keratinocytes and dermal fibroblasts to the human mast cell proteases tryptase and chymase was evaluated. PAR activat