Interactions of amiodarone with model membranes and amiodarone-photoinduced peroxidation of lipids
✍ Scribed by Anne-Marie Sautereau; Cécile Tournaire; Monique Suares; Jean-Francois Tocanne; Nicole Paillous
- Book ID
- 115782662
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 965 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0006-2952
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📜 SIMILAR VOLUMES
Amiodarone is an iodinated benzofuran derivative largely used as an antiarrhythmic. Owing to the sensitivity of heart tissue to radicals, amiodarone was assayed for putative eects on lipid peroxidation studied in liposomes of soybean phosphatidylcholine and of bovine heart mitochondrial lipids used
The eects of amiodarone (AMD) on lipid peroxidation of rat liver mitochondria, the formation of superoxide anions at the respiratory chain level, and the cytosolic and mitochondrial enzymatic protective mechanisms of oxidative stress were studied. An attempt of classify AMD according to its toxic ab