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Interactions Between the Host Innate Immune System and Microbes in Inflammatory Bowel Disease

✍ Scribed by Clara Abraham; Ruslan Medzhitov


Book ID
119761883
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
969 KB
Volume
140
Category
Article
ISSN
0016-5085

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The discovery of nucleotide-binding oligomerization domain 2/caspase recruitment domain-containing protein 15 (NOD2/CARD15) as the first susceptibility gene in Crohn's disease (CD) has shifted the focus of research into the pathogenesis of inflammatory bowel disease (IBD) firmly to the innate immune