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Inflammatory bowel disease requires the interplay between innate and adaptive immune signals

✍ Scribed by Shi, Dayna; Das, Jyoti; Das, Gobardhan


Book ID
110020712
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
625 KB
Volume
16
Category
Article
ISSN
0007-0610

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The discovery of nucleotide-binding oligomerization domain 2/caspase recruitment domain-containing protein 15 (NOD2/CARD15) as the first susceptibility gene in Crohn's disease (CD) has shifted the focus of research into the pathogenesis of inflammatory bowel disease (IBD) firmly to the innate immune