Interactions between Glutathione-S-Transferase M1, T1 and P1 polymorphisms and smoking, and increased susceptibility to esophageal squamous cell carcinoma
✍ Scribed by Omeed Moaven; Hamid Reza Raziee; Hamid Reza Sima; Azita Ganji; Reza Malekzadeh; Azadeh A’rabi; Abbas Abdollahi; Bahram Memar; Masoud Sotoudeh; Hossein Naseh; Navid Nekoui; Adeleh Razavipour; Mehran Gholamin; Ezzat Dadkhah; Moein Farshchian; Mohammad Reza Abbaszadegan
- Book ID
- 108078818
- Publisher
- Elsevier
- Year
- 2010
- Tongue
- English
- Weight
- 514 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1877-7821
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📜 SIMILAR VOLUMES
Glutathione S-transferases (GSTs) belong to a superfamily of detoxification enzymes that provide critical defences against a large variety of chemical carcinogens and environmental toxicants. GSTs are present in most epithelial tissues of the human gastrointestinal tract. We investigated association
We examined the effect of genetic polymorphisms of phase-II enzymes, glutathione S-transferase P1 (GSTP1) and N-acetyltrans-ferase2 (NAT2) on susceptibility to esophageal squamous-cell carcinoma. To determine the genotypes of the 2 polymorphisms, PCR-based analysis was performed on samples from 66 J