Activation of cytochrome P450IA1 gene ex
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Margaret A. Hirst; Keith W. Jones; James P. Whitlock Jr.
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Article
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1989
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John Wiley and Sons
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English
⚖ 666 KB
We analyzed the function of a DNA domain located upstream of the cytochrome P4501A1 gene in wild-type (Hepa lclc7) mouse hepatoma cells and in high-activityvariant (HAV) cells that overtranscribe the gene in response to the inducer 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Transfection experiments