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Interactions between Cancer and Bone Marrow Cells Induce Osteoclast Differentiation Factor Expression and Osteoclast-like Cell Formation in Vitro

โœ Scribed by Noriko Chikatsu; Yasuhiro Takeuchi; Yasuhiro Tamura; Seiji Fukumoto; Kazuki Yano; Eisuke Tsuda; Etsuro Ogata; Toshiro Fujita

Book ID
115585099
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
92 KB
Volume
267
Category
Article
ISSN
0006-291X

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## Abstract Prostate cancer (PCa) preferentially metastasizes to bone resulting in osteoblastic lesions with underlying osteolytic activities. The mechanisms through which PCa cells promote osteolytic activities and subsequent osteoblastic bone formation remain poorly understood. Parathyroid hormon