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Expression of IL-6 Receptor and GP130 in Mouse Bone Marrow Cells During Osteoclast Differentiation

โœ Scribed by Y Gao; I Morita; N Maruo; T Kubota; S Murota; T Aso

Book ID
117808587
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
444 KB
Volume
22
Category
Article
ISSN
8756-3282

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-type cytokines stimulate osteoclast formation by activating the glycoprotein 130 (gp130) receptor subunit on stromal/osteoblastic cells, which in turn leads to signal transducer and activator of transcription 3 (STAT3)-mediated expression of receptor activator of NF-B ligand (RANKL). Based on evide