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Interaction study of ciprofloxacin with human telomeric DNA by spectroscopy and molecular docking

✍ Scribed by Li, Huihui; Bu, Xiaoyang; Lu, Jia; Xu, Chongzheng; Wang, Xianlong; Yang, Xiaodi

Book ID
120486462
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
572 KB
Volume
107
Category
Article
ISSN
1386-1425

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We have performed a study by electronic spectroscopy and molecular docking simulation of the interaction of terthiophene with DNA, modelled as short oligonucleotide sequences containing either the guanine-cytosine or the adenine-thymine motif. We demonstrated that the presence of TT gives rise to a