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Spectroscopic and molecular docking studies on chlorambucil interaction with DNA

✍ Scribed by Sonika Charak; Manish Shandilya; Gunjan Tyagi; Ranjana Mehrotra


Book ID
119261117
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
707 KB
Volume
51
Category
Article
ISSN
0141-8130

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We have performed a study by electronic spectroscopy and molecular docking simulation of the interaction of terthiophene with DNA, modelled as short oligonucleotide sequences containing either the guanine-cytosine or the adenine-thymine motif. We demonstrated that the presence of TT gives rise to a