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Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex

✍ Scribed by Pollard, Thomas D.; Marchand, Jean-Baptiste; Kaiser, Donald A.; Higgs, Henry N.


Book ID
109773074
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
686 KB
Volume
3
Category
Article
ISSN
1465-7392

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## Abstract The WAVE/Scar proteins regulate actin polymerisation at the leading edge of motile cells via activation of the Arp2/3 complex in response to extracellular cues. Within cells they form part of a pentameric complex that is thought to regulate their ability to interact and activate the Arp