Spatial and temporal regulation of actin polymerization for cytoskeleton formation through Arp2/3 complex and WASP/WAVE proteins

The actin nucleating Arp2/3 complex cont

The actin nucleating Arp2/3 complex contributes to the formation of axonal filopodia and branches through the regulation of actin patch precursors to filopodia

✍ Mirela Spillane; Andrea Ketschek; Steven L. Jones; Farida Korobova; Bonnie Marsi 📂 Article 📅 2011 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 536 KB

## Abstract The emergence of axonal filopodia is the first step in the formation of axon collateral branches. __In vitro__, axonal filopodia emerge from precursor cytoskeletal structures termed actin patches. However, nothing is known about the cytoskeletal dynamics of the axon leading to the forma