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Interaction of valproic acid and some analogues with microsomal epoxide hydrolase

✍ Scribed by Doris K. Robbins; Peter J. Wedlund; Sabine Elsberg; Franz Oesch; Helmut Thomas


Book ID
115782733
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
868 KB
Volume
43
Category
Article
ISSN
0006-2952

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Induction of microsomal epoxide hydrolas
✍ R. Sellman; M. G. Parkki πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 English βš– 405 KB πŸ‘ 1 views

The effects of tienilic acid [ 2,3-dichloro-4-(2-thienylcarbonyl)phenoxy acetic acid] on drug-metabolizing enzymes in the rat liver and kidneys were studied. Short-term treatment for 2 weeks (450 mg per kg per day) increased the activity of microsomal epoxide hydrolase at least two-fold in both rat