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Structure Activity Relationship of Human Microsomal Epoxide Hydrolase Inhibition by Amide and Acid Analogues of Valproic Acid

✍ Scribed by Ofer Spiegelstein; Deanna L. Kroetz; René H. Levy; Boris Yagen; Sussan I. Hurst; Micha Levi; Abdulla Haj-Yehia; Meir Bialer

Book ID
110251807
Publisher
Springer US
Year
2000
Tongue
English
Weight
52 KB
Volume
17
Category
Article
ISSN
0724-8741

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Quantitative structure–activity relation
Quantitative structure–activity relationship study on the inhibitors of fatty acid amide hydrolase
✍ Peng Lu; Ruisheng Zhang; Yongna Yuan; Zhiguo Gong 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 345 KB 👁 2 views

## Abstract A quantitative structure activity relationship (QSAR) analysis was performed on the $K\_i $ values of a series of fatty acid amide hydrolase (FAAH) inhibitors. Six molecular descriptors selected by CODESSA software were used as inputs to perform heuristic method (HM) and support vector