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Interaction of SCH 23390, a D-1-selective antagonist, with the anterior pituitary D-2 receptors and prolactin secretion in the rat

✍ Scribed by JoséAntonio Apud; Claudio Masotto; Ennio Ongini; Giorgio Racagni

Book ID
115879402
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
470 KB
Volume
112
Category
Article
ISSN
0014-2999

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Characterization of the binding of 3H-SCH 23390, a selective D-1 receptor antagonist ligand, in rat striatum
✍ William Billard; Vilma Ruperto; Gordon Crosby; Louis C. Iorio; Allen Barnett 📂 Article 📅 1984 🏛 Elsevier Science 🌐 English ⚖ 398 KB

A novel benzazepine, SCH 23390, has recently been described as a very potent and selective dopamine D-1 receptor antagonist based on its potent inhibition of dopamine sensitive adenylate cyclase and its selective displacement of 3H-piflutixol from rat striatal receptor sites. In the present study, t