Interaction of Pt(II) complexes with DNAs from various sources. A circular dichroism study
β Scribed by A.M. Tamburro; L. Celotti; D. Furlan; V. Guantieri
- Book ID
- 113135832
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- English
- Weight
- 493 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0009-2797
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The volume changes, AV. produced by the formation of two types of 1:l Cu(Ii)rdipeptide complexes were determined dilatometrically. A volume increase of about 11 ml/mole results from the formation of one category of complex in which the Cu(II) is chelated to the terminal amino and carbonyl oxygen of
## Abstract Inspired by naturally occurring DNAβbinding proteins and their artificial __Ξ±__βpeptidic mimics reported to date, a research project was initiated aiming at creating a new class of __Ξ²__βpeptides capable of binding to and ultimately regulating the functions of DNA. As an initial foray,