Phosphorylation of ribonucleosides with
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M. Honjo; R. Marumoto; K. Kobayashi; Y. Yoshioka
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Article
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1966
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Elsevier Science
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French
β 215 KB
The reaction between a" alcohol and a large excess of PC13 generally gives a dichlorophosphite, which on hydrolysis affords a phosphite. Thus, treatment of a" Ip\* ribonucleoside with PC13 should give, after hydrolysis and de-blocking the protective group, a ribonucleoside-5'-phosphite. Contrary to