The present study was designed to characterize the cross-talk of parathyroid hormone (PTH)-responsive dual signal transduction systems (CAMP-dependent protein kinase (PKA) and calcium/protein kinase C [PKCI) and its participation in PTH-induced homologous desensitization of intracellular calcium ([C
Interaction of parathyroid hormone-related peptide-responsive dual signal transduction systems in osteoblastic osteosarcoma cells: Role in PTHrP-induced homologous desensitization
โ Scribed by Toshitsugu Sugimoto; Junichi Kano; Kazuto Ikeda; Masaaki Fukase; Kazuo Chihara
- Book ID
- 112119060
- Publisher
- American Society for Bone and Mineral Research
- Year
- 2009
- Tongue
- English
- Weight
- 689 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0884-0431
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## Abstract The present study was performed to clarify second messenger signaling in parathyroid hormone (PTH)โinduced cโfos gene expression, to characterize the participation of the cโfos gene in the regulation of osteoblast proliferation and function as well as osteoclastโlike cell formation by P
## Abstract The present study was performed to investigate the regulation of cytosolic pH (pHi) and DNA synthesis by parathyroid hormone(PTH) and PTHโrelated peptide (PTHrP) in osteoblasts, using osteoblastic osteosarcoma cells, UMRโ106 which possessed PTHโresponsive dual signal transduction system