Interaction of mercury(II) with the microtubule cytoskeleton in IMR-32 neuroblastoma cells
โ Scribed by Thomas Stoiber; Gisela H Degen; Hermann M Bolt; Eberhard Unger
- Book ID
- 119377774
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 368 KB
- Volume
- 151
- Category
- Article
- ISSN
- 0378-4274
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Neuroblastoma (NB) is the most common solid pediatric tumor. IMR-32 cells are a highly malignant human NB cell line with uncontrolled proliferation but with the potential to be differentiated under specific conditions. Preliminary research indicated that connexin 43 (Cx43), the most widespread of th
The gamma-aminobutyric acid (GABA) response profiles of IMR-32 human neuroblastoma cells were examined using whole-cell patch clamp and RT-PCR techniques. GABA activated a concentration-dependent and bicuculline-sensitive current, and RT-PCR revealed the expression of multiple GABA(A) receptor subun