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Identification of the GABAA Receptor α3 Subunit in the IMR-32 Neuroblastoma Cell Line

✍ Scribed by Penelope J. Noble; Shelagh M. P. Anderson; Rosemarie J. De Souza; Alan J. Cross; F. Anne Stephenson


Book ID
111177716
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
501 KB
Volume
61
Category
Article
ISSN
0022-3042

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The gamma-aminobutyric acid (GABA) response profiles of IMR-32 human neuroblastoma cells were examined using whole-cell patch clamp and RT-PCR techniques. GABA activated a concentration-dependent and bicuculline-sensitive current, and RT-PCR revealed the expression of multiple GABA(A) receptor subun