Interaction of Magainin 2 with Gangliosides as a Target for Human Cell Binding
โ Scribed by Miyazaki, Yu; Yano, Yoshiaki; Matsuzaki, Katsumi
- Book ID
- 122181218
- Publisher
- Biophysical Society
- Year
- 2013
- Tongue
- English
- Weight
- 70 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0006-3495
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This report investigates the possibility that the ganglioside GM2 is a common target structure for natural killer cells. A subpop-ulation of lymphocytes, NK cells may play a role in vivo in controlling the growth of certain tumors.
Although human N K cells lyse a wide spectrum of target cells, the precise target structure recognized by N K cells has not yet been elucidated. In order to define a possible relationship between gangliosides on human target cells and susceptibility to N K lysis. 14 human leukemia and lymphoma cell