Although human N K cells lyse a wide spectrum of target cells, the precise target structure recognized by N K cells has not yet been elucidated. In order to define a possible relationship between gangliosides on human target cells and susceptibility to N K lysis. 14 human leukemia and lymphoma cell
β¦ LIBER β¦
Ganglioside gm2 as a target structure recognized by human natural killer cells
β Scribed by Iwao Ando; Dave B. Hoon; Sidney H. Golub; Rieko F. Irie; Paul K. Pattengale
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 600 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0887-8013
No coin nor oath required. For personal study only.
β¦ Synopsis
This report investigates the possibility that the ganglioside GM2 is a common target structure for natural killer cells. A subpop-ulation of lymphocytes, NK cells may play a role in vivo in controlling the growth of certain tumors.
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