Interaction of Hypericin with Serum Albumins: Surface-enhanced Raman Spectroscopy, Resonance Raman Spectroscopy and Molecular Modeling Study
β Scribed by Pavol Miskovsky; Jozef Hritz; Santiago Sanchez-Cortes; Gabriela Fabriciova; Jozef Ulicny; Laurent Chinsky
- Book ID
- 111836704
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 904 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0031-8655
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## Abstract Surfaceβenhanced Raman spectroscopy was employed in this work to study the interaction between the antitumoral drug emodin and human serum albumin (HSA), as well as the influence of fatty acids in this interaction. We demonstrated that the drug/protein interaction can take place through
The interactions of doxorubicin and its derivatives, hydroxyrubicin and adriamycinone, with DNA were studied by resonance Raman (RR) and surface-enhanced resonance Raman scattering (SERRS) spectroscopy. The p-p interaction between the chromophore of the drug and DNA base pairs has been shown to down
## SYNOPSIS SERS, SERRS and NIR FTSERS of emodin and hypericin are reported for the first time on aqueous silver colloid. Intense SERRS spectra can be obtained when using excitation lines at 514 nm for emodin and 598 nm for hypericin. FTIR and NIR FTRaman spectra from these molecules and their mod