Interaction of human PD-L1 and B7-1
✍ Scribed by Manish J. Butte; Victor Peña-Cruz; Mi-Jung Kim; Gordon J. Freeman; Arlene H. Sharpe
- Book ID
- 116756865
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 794 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0161-5890
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Expression by DCs of co‐inhibitory molecules such as programmed death ligand‐1 (PD‐L1/B7‐H1/CD274), a member of the B7 superfamily, is crucial for the downregulation of T‐cell responses and the maintenance of immune homeostasis. Exposure of immature DCs to danger‐associated molecular pa
## Abstract Human tumors frequently escape immune destruction, despite the presence of cyototoxic T cells (CTL) recognizing tumor‐associated antigens (TAA). We have previously shown that programmed death ligand‐1 (PD‐L1), a recently identified ligand of the B7 superfamily, is expressed on murine tu