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Interaction of Fibroblast Growth Factor-1 and Related Peptides with Heparan Sulfate and Its Oligosaccharides

✍ Scribed by Jonathan R. Fromm; Ronald E. Hileman; John M. Weiler; Robert J. Linhardt

Book ID
115566693
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
277 KB
Volume
346
Category
Article
ISSN
0003-9861

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Heparan sulfate proteoglycans (HSPGs) are ubiquitous macromolecules associated with the cell surface and extracellular matrix (ECM) of a wide range of cells of vertebrate and invertebrate tissues [1,2]. The basic HSPG structure consists of a protein core to which several linear heparan sulfate (HS)