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Mitogenic activity of acidic fibroblast growth factor is enhanced by highly sulfated oligosaccharides derived from heparin and heparan sulfate

โœ Scribed by Angelo G. Gambarini; Catarina A. Miyamoto; Geovani A. Lima; Helena B. Nader; Carl P. Dietrich

Publisher
Springer
Year
1993
Tongue
English
Weight
831 KB
Volume
124
Category
Article
ISSN
0300-8177

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๐Ÿ“œ SIMILAR VOLUMES

Acidic and basic fibroblast growth facto
Acidic and basic fibroblast growth factor bind with differing affinity to the same heparan sulfate proteoglycan on BALB/c 3T3 cells: Implications for potentiation of growth factor action by heparin
โœ Kathryn J. Brown; Ian A. Hendry; Christopher R. Parish ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 806 KB

Heparan sulfate proteoglycans on the cell surface act as low affinity binding sites for acidic and basic fibroblast growth factor (FGF) [Moscatelli (1987): J Cell Physiol 131:123-1301 and play an important role in the interaction of FGF with the FGF receptor (FGFR). In this study, several aspects of