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Interaction of Epstein-Barr virus DNA polymerase with aphidicolin, phosphonoformate and 5′-GMP

✍ Scribed by Jin-Sen Li; Yung-Chi Cheng


Book ID
104686941
Publisher
Springer
Year
1988
Tongue
English
Weight
357 KB
Volume
1
Category
Article
ISSN
0920-8569

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A salt-dependent DNA polymerase activity was demonstrated in the culture of an EBV-producing, lymphoblastoid cell line (NPC-204 cells) treated with 5-iodo-2'-deoxyuridine (IUdR). There was a high frequency of levels of antibody to this enzyme in sera of patients with nasopharyngeal carcinoma (NPC).