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Interaction of Artemisinins with Oxyhemoglobin Hb–FeII, Hb–FeII, CarboxyHb–FeII, Heme–FeII, and Carboxyheme FeII: Significance for Mode of Action and Implications for Therapy of Cerebral Malaria

✍ Scribed by Paolo Coghi; Nicoletta Basilico; Donatella Taramelli; Wing-Chi Chan; Richard K. Haynes; Diego Monti

Book ID
102806160
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
630 KB
Volume
4
Category
Article
ISSN
1860-7179

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Cover Picture: Interaction of Artemisini
Cover Picture: Interaction of Artemisinins with Oxyhemoglobin Hb–FeII, Hb–FeII, CarboxyHb–FeII, Heme–FeII, and Carboxyheme FeII: Significance for Mode of Action and Implications for Therapy of Cerebral Malaria (ChemMedChem 12/2009)
✍ Paolo Coghi; Nicoletta Basilico; Donatella Taramelli; Wing-Chi Chan; Richard K. 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 835 KB

The cover picture shows erythrocytes infected with malaria parasites after Giemsa staining (background). Heme, either within the hemoglobin (Hb) (ribbon diagram) or produced by catabolism of the Hb by the parasite, is considered to be responsible for the antimalarial activity of artemisinins (genera