Zanamivir (ZAN) is the first of a new generation of influenza virus-specific drugs known as neuraminidase inhibitors, which acts by interfering with life cycles of influenza viruses A and B. It prevents the virus spreading infection to other cells by blocking the neuraminidase enzyme present on the
Interaction of antitumor drug Sn(CH3)2Cl2 with DNA and RNA
β Scribed by Shohreh Nafisi; Amir Sobhanmanesh; Majid Esm-Hosseini; Kamran Alimoghaddam; Heidar Ali Tajmir-Riahi
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 329 KB
- Volume
- 750
- Category
- Article
- ISSN
- 0022-2860
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Some new diorganotin(IV) complexes of heterocyclic dithiocarbamate having general formula R 2 Sn(Cl)S 2 CNR 2 and R 2 Sn(S 2 CNR 2 ) 2 [R = 2-F-Bz, 3-Cl-Bz; NR 2 = N(CH 2 CH 2 ) 2 NMe, N(CH 2 CH 2 ) 2 NEt, and N(CH 2 CH 2 ) 2 NBz] have been prepared, respectively. Elemental analyses, IR, and NMR spe
In the present study the nature and the hydrolysis of DNA-I% complexes with the platinum compounds, [Pt(dien)C1]Cl, Imns-and ~rlrPt(NH~),Ci,, using potentiometric chloride determinations, have been investigated. The tmns-Pt(NH,),C1, and the [Pt(dien)Cl] Cl react with the GC planes at the N,(G) sites
Rate constants for the reactions of OH radicals and Cl atoms with CH,CH,NO>, CH,CH,CH,NO,, CH3CH2CH2CHzN02, and CH,CH2CH2CH,CH2N02 have been determined at 295+3 K and a total pressure of approximately 1 atm. The OH rate data were obtained using both the absolute rate technique of pulse radiolysis co
The equilibrium geometry of the title compound, which serves as a model for Ti (dmpe)C13CH3, has been obtained by means of SCF and MP2 calculations. The computed MP2 geometry is in excellent agreement with experimental neutron diffraction data. The crucial angle Ti-C-H of 93.5 Β° that led previous wo