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Interaction of 5-methoxy-1,2,4-triazines with ureas as a new route to 6-azapurines

โœ Scribed by Dmitry G. Beresnev; Gennady L. Rusinov; Oleg N. Chupakhin; Hans Neunhoeffer

Book ID
111730256
Publisher
Royal Society of Chemistry
Year
2000
Tongue
English
Weight
85 KB
Volume
10
Category
Article
ISSN
0959-9436

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โœ S.G. Alexeev; V.N. Charushin; O.N. Chupakhin; G.G. Alexandrov ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 226 KB

The reaction of 1,2,4-triazinium salts with amides of acetoacetic acid yielding ,7,7a-hexahydro-6H-pyrrolo[3,2-e]-1,2,4-triazin-6-ones exemplifies the first direct to the 1,2,4-triazine ring based on the diaddition of bifunctional nucleophiles at C-5 and C-6.