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Interaction of 1,3-di(2-[5-3H]tolyl)guanidine with σ2 binding sites in rat heart membrane preparations

✍ Scribed by Michel Dumont; Simon Lemaire

Book ID: 115886726
Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 330 KB
Volume: 209
Category: Article
ISSN: 0014-2999
DOI: 10.1016/0014-2999(91)90176-q

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## Abstract The aim of the present study was to find out if a cell line of glial origin possesses sigma and/or phencyclidine (PCP) binding sites. Binding of [^3^H]1,3‐di‐o‐tolyl‐guanidine (DTG), a highly selective ligand for sigma binding sites, and of [^3^H]N‐[1‐(2‐thienyl)cyclohexyl] piperidine (