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Interaction between ubiquitin–protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

✍ Scribed by Krek, W.; Marti, A.; Wirbelauer, C.; Scheffner, M.


Book ID
109831902
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
355 KB
Volume
1
Category
Article
ISSN
1465-7392

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Pura is a ubiquitously expressed multifunctional nucleic acid-binding protein that is involved in many cellular processes including transcriptional regulation, the cell cycle, oncogenic transformation, and post-natal brain development. Previously, Pura protein was found to bind to E2F-1, inhibit E2F