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Interaction between Smad Anchor for Receptor Activation and Smad3 Is Not Essential for TGF-β/Smad3-Mediated Signaling

✍ Scribed by Daisuke Goto; Hiroshi Nakajima; Yumiko Mori; Kazuhiro Kurasawa; Naomi Kitamura; Itsuo Iwamoto


Book ID
115587571
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
148 KB
Volume
281
Category
Article
ISSN
0006-291X

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Interaction of Smad3 with a proximal sma
✍ Shu-Jen Chen; Weihua Yuan; Sientay Lo; Maria Trojanowska; John Varga 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 264 KB 👁 1 views

Transcription of the alpha2(I) collagen gene (COL1A2) in fibroblasts is potently induced by transforming growth factor-beta (TGF-beta). Smad family proteins function as intracellular signal transducers for TGF-beta that convey information from the cell membrane to the nucleus. In the present study,