Interaction between poly(amidoamine) dendrimers and DNA studied by spectroscopic methods
β Scribed by Yanming Wang; Yu Song; Deling Kong; Yaoting Yu
- Book ID
- 105726892
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 364 KB
- Volume
- 50
- Category
- Article
- ISSN
- 1001-6538
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The interactions between phenylbutazone, a well-established nonsteroidal anti-inflammatory drug, with different generations of poly(amidoamine) (PAMAM) dendrimers, have been investigated by aqueous solubility, two dimensional nuclear Overhauser effect spectroscopy (2D-NOESY) and isothermal titration
## Abstract We have shown previously that glycyrol has an inhibitory effect on the immune response in mice by reducing calcineurin activity (Li et al., 2010, Pharm Biol 48:1177β1184). Here, we investigated the interaction of glycyrol with calcineurin A (CNA, catalytic A subunit of calcineurin) by s