✦ LIBER ✦

Interaction between phosphatidylcholine and cholesterol in benzene

✍ Scribed by J.P.M. Janson; M. Kunst; A. Rip; P. Bordewijk

Publisher: Elsevier Science
Year: 1973
Tongue: English
Weight: 506 KB
Volume: 10
Category: Article
ISSN: 0009-3084
DOI: 10.1016/0009-3084(73)90045-5

No coin nor oath required. For personal study only.

✦ Synopsis

The interaction between phosphatidylcholine (PC) and cholesterol was studied in benzene with the help of vapour-pressure osmometry and static dielectric measurements. No indication for the occurrence of molecular complexes was found. Instead, our results can be explained by assuming PC aggregates (as found in a previous study) with a constant number of PC molecules, on which cholesterol molecules are adsorbed independently of each other. The maximum number of cholesterol molecules that can be adsorbed by the PC aggregate is equal to the number of PC molecules in the aggregate or higher.

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