The hydration characteristics of phosphatidylcholines and the effect of cholesterol on these were studied with differential thermal analysis and water vapour adsorption experiments. Also the water adsorption of egg phosphatidylethanolamine and the effect of cholesterol on this was studied and compar
Interaction between cholesterol and phospholipid in hydrated bilayers
β Scribed by J.B. Finean
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 907 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0009-3084
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β¦ Synopsis
The widely-supported proposal that the addition of cholesterol to phospholipid in hydrated systems generates a physical state intermediate between liquid crystalline and gel and thereby eliminates the characteristic phospholipid liquid crystalline--gel phase transition is re-examined in relation to recent extensions of X-ray diffraction studies to cover a wider range of phospholipids.
π SIMILAR VOLUMES
To extend our knowledge of model membrane systems based upon one lipid component, multi-lamellar bilayers were made of cholesterol with two phospholipids in equimolar ratio, and the enthalpy change AH of the main phase transition of the ternary mixture was measured by differential scanning calorimet