Interaction between lysine-rich histones and DNA
β Scribed by Christina Iovcheva; George N. Dessev
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 337 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0301-4851
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Most procedures for the isolation of DNA have been designed for the extraction of this material from calf thymus glands. Difficulties are, however, encountered when similar procedures are applied to isolate DNA from tissues such as rat and mouse liver, since the DNA is usually contaminated with RNA,
## Abstract Poly(Lys^48^, His^52^), a random copolypeptide of Lβlysine (48%) and Lβhistidine (52%), was used as a model protein for investigating the effects of protonation on the imidazole group of histidines on protein binding to DNA. The complexes formed between poly(Lys^48^, His^52^) and DNA we