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Interaction between Insulin and AT1receptor. Relevance for hypertension and arteriosclerosis

✍ Scribed by G. Nickenig; M. Böhm


Book ID
106067549
Publisher
Springer
Year
1998
Tongue
English
Weight
120 KB
Volume
93
Category
Article
ISSN
0300-8428

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## Abstract The insulin receptor substrate‐1 (IRS‐1) and c‐met, the receptor for the hepatocyte growth factor (HGF) co‐immuno‐precipitate from lysates treated with the respective antibodies. The interaction between IRS‐1 and c‐met requires a tyrosyl phosphorylated IRS‐1 and results in reciprocal do