Mutual interaction and reciprocal down-r
✍
Tiziana DeAngelis; Andrea Morrione; Renato Baserga
📂
Article
📅
2010
🏛
John Wiley and Sons
🌐
English
⚖ 197 KB
## Abstract The insulin receptor substrate‐1 (IRS‐1) and c‐met, the receptor for the hepatocyte growth factor (HGF) co‐immuno‐precipitate from lysates treated with the respective antibodies. The interaction between IRS‐1 and c‐met requires a tyrosyl phosphorylated IRS‐1 and results in reciprocal do