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Integrators of the Cytoskeleton that Stabilize Microtubules

✍ Scribed by Yanmin Yang; Christoph Bauer; Geraldine Strasser; Robert Wollman; Jean-Pierre Julien; Elaine Fuchs

Book ID
117267914
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
604 KB
Volume
98
Category
Article
ISSN
0092-8674

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Microtubules are specifically and efficiently visualized with the new fluorescent taxoids 7-O-[N-(4'-fluoresceincarbonyl)-L-alanyl]taxol (FLUTAX) and 7-O-[N-(4'-tetramethylrhodaminecarbonyl)-L-alanyl]taxol (ROTAX). Similarly to taxol, FLUTAX and ROTAX are able to drive inactive GDP-liganded tubulin