Integration of Hormonal Agents and Chemotherapy for the Treatment of Women With Advanced Breast Cancer
β Scribed by INGLE, JAMES N.
- Book ID
- 122906430
- Publisher
- Mayo Clinic
- Year
- 1984
- Tongue
- English
- Weight
- 612 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0025-6196
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π SIMILAR VOLUMES
## Abstract Seventyβtwo women with metastatic breast cancer were treated with multipleβagent chemotherapy. Fifty women were treated with 5 drugs in combination: 5βFU, methotrexate, vincristine, cytoxan, and prednisone; 22 were treated with the combination of 3 drugs: 5βFU, cytoxan, and prednisone.
Repeated administration of long-acting analogues of gonadotrophin-releasing hormone down-regulates the pituitary gonadotrophins and gonadal hormones. The activity of these compounds in premenopausal women with breast cancer has been previously noted. In an attempt to cause a highly selective medical