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Integration of chemotherapy in an MFD-radiotherapy plan for advanced inoperable squamous cell carcinoma of the head and neck

✍ Scribed by Tideman, H.

Book ID
122372984
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
112 KB
Volume
19
Category
Article
ISSN
0901-5027

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Integration of chemotherapy in an MFD-ra
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patients with advanced squamous cell carcinoma of the head and neck received combined treatment, based on an alternating schedule of chemotherapy and multiple fractions per day (MFD)-radiotherapy. The chemotherapy regimen consisted of cisplatin, 20 mg/m2, followed by 5-fluorouracil (5-FU), 200 mg/m2

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Patients with locally advanced, inoperable squamous cell carcinoma of the head and neck were offered three courses of cisplatin and 96-h 5-fluorouracil (5-FU) infusion. Subsequent therapy included surgery when feasible, irradiation therapy, and a maintenance program of methotrexate (MTX)-5-FU. Thirt