𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Integration of breast MRI in clinical trials

✍ Scribed by Steven E. Harms

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
240 KB
Volume
13
Category
Article
ISSN
1053-1807

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Clinical trials are the mechanism for implementing new treatment methods into clinical practice. A number of organizations have been developed to facilitate the initiation, implementation, and data analysis for clinical trials. Imaging is important for patient selection and establishment of endpoints, yet imaging expertise has been underrepresented in most clinical trial groups. The integration of breast MRI in clinical trials is an important step toward the establishment of this method of imaging in routine practice. In addition, these data will be important in justifying the expense of MRI to payer organizations. The potential roles of breast MRI in clinical trials are reviewed. These breast MRI applications are linked with some of the studies that are under development. It is important for the MRI community to be aware of the importance of clinical trials in the future clinical establishment of breast MRI. J. Magn. Reson. Imaging 2001;13:830–836. Β© 2001 Wiley‐Liss, Inc.

πŸ“œ SIMILAR VOLUMES

MRI of atherosclerosis in clinical trial
MRI of atherosclerosis in clinical trials
✍ Chun Yuan; William S. Kerwin; Vasily L. Yarnykh; Jianming Cai; Tobias Saam; Baoc πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 499 KB

Magnetic resonance imaging (MRI) of the arterial wall has emerged as a viable technology for characterizing atherosclerotic lesions in vivo, especially within carotid arteries and other large vessels. This capability has facilitated the use of carotid MRI in clinical trials to evaluate therapeutic e

MRI: A role in clinical trials
MRI: A role in clinical trials
✍ Thomas B. Julian πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 63 KB

## Abstract The diagnosis and treatment of breast cancer has evolved significantly over the last 20 years. Breast‐conserving therapy is replacing the Halstedian concept of β€œen bloc” resection. Difficulties in detection, pre‐ and postoperative planning and follow up continue to challenge the clinici

Clinical trial of nafoxidine in advanced
Clinical trial of nafoxidine in advanced breast cancer
✍ Steinbaum, Fred L. ;de Jager, Robert L. ;Krakoff, Irwin H. πŸ“‚ Article πŸ“… 1978 πŸ› John Wiley and Sons 🌐 English βš– 198 KB

Forty-nine postmenopausal patients with advanced breast cancer were treated with a nonsteroidal antiestrogen, Nafoxidine. The drug was generally well tolerated with dermatitis being the major toxic effect. A partial response in 12 of 40 patients, or 30%, was achieved with a median duration of respon